Within the framework of our International Graduate Program, we offer 6 PhD student positions in the cutting-edge research fields of immune regulation, cancer immunotherapy and T cell-engineering. Participating chairs and groups include the Chair of Genetic-Immunotherapy (Prof. Abken), the Chair of Interventional Immunology (Prof. Beckhove), the Chair of Immunology (Prof. Feuerer), the Chair of Functional Immune Cell Modulation (Prof. Gattinoni) and the Research Groups “Immune Regulation” (PD Dr. Hoffmann) and “Organ Transplantation” (Prof. Geissler).
Our groups are interested in investigating the mechanisms underlying the complex interplay between immune and malignant cells, resulting in the control and eradication of cancer. With the help of state-of-the-art methods such as long term live cell imaging, single-cell RNA-sequencing and transcriptome analysis, chromatin immunoprecipitation, chromatin accessibility mapping and CRISPR genome editing, CAR and other recombinant immune cell receptors etc., we are aiming to reveal the molecular basis of effective immune responses to malignancies. In addition, we are working on projects that utilize the obtained knowledge and using T cell-engineering we aim to generate T cells that have superior anti-tumor activity.
Furthermore, we work on projects focusing on mechanisms of immune regulation and tumor destruction, studying the pathways utilized by immune cells to control immune responses. Regulatory T cells (Treg) maintain self-tolerance, thereby affecting a variety of conditions, including cancer, autoimmunity, and inflammation.
We are looking for highly motivated and enthusiastic individuals, able to work independently as well as a part of an interdisciplinary team. Master/Diplom- or equivalent degree in biology, biochemistry, biomedicine or closely related subject is required. Strong background in cell and molecular biology, a keen interest in the immune system and molecular mechanisms, and the aspiration to learn and work with state-of-the-art techniques is essential. Furthermore, excellent oral and written communication skills in English are mandatory.
What we offer:
We offer the opportunity to work at the interface of immunology, cancer, and auto-immune diseases, which is one of the most exciting fields of recent biomedical research. We provide a dynamic and motivating working environment where you can foster your skills and get the opportunity to learn cutting-edge techniques. We offer excellent mentoring and the opportunity to contribute and develop own ideas. The positions are available for 3 years, with the possibility of prolongation. The post is remunerated on the TV-L salary scale (TV-L E13, 65%).
If we have awakened your interest and you are open to new professional challenges, we would be delighted to receive an informative application.
Please send your full applications (including curriculum vitae, a letter of motivation, certificates, expected availability date, a list of publications, and 2-3 references) in a single pdf-file (reference number IGP-2020-1) by email to Ms. Sabine Repp, bewerbungen.rci(at)ukr.de. Application deadline is March 1st, 2020.